MolNFT v1 · #138788 · protein

Crystal structure of GH57-type branching enzyme from hyperthermophilic archaeon pyrococcus horikoshii

5WU7 · Uncharacterized protein: “Crystal structure of GH57-type branching enzyme from hyperthermophilic archaeon pyrococcus horikoshii”. X-ray diffraction, 8 pockets (best druggability 0.75). MolNFT v1 #138788 on GenesisL1: 3D structure…

PDB: 5WU7
Type: protein
Length: 1,066 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein
UniProt: O50094
Pockets: 8 · best druggability 0.75

Structure

x-ray diffraction · 2 distinct chains · 52% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein	protein	530	52% helix, 12% strand	O50094
B	Uncharacterized protein	protein	536	52% helix, 12% strand	O50094

Ligands and binding sites

GOL · Glycerol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	676	0.75	0.81	59	GOL
2	578	0.72	0.80	66	GOL
3	365	0.62	0.78	35	empty
4	114	0.45	0.78	23	empty
5	86	0.43	0.79	24	empty

Interfaces

1 interface between chains.

A–B · 613 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

5WU7 · Crystal structure of GH57-type branching enzyme from hyperthermophilic archaeon… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O50094
Elsewhere: RCSB PDB 5WU7 · PDBe 5WU7 · UniProt O50094

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