MolNFT v1 · #138770 · protein
Crystal structure analysis of primosome protein dnab (resiues 1-300) from geobacillus stearothermophilus
5WTN · Replication initiation and membrane attachment protein: “Crystal structure analysis of primosome protein dnab (resiues 1-300) from geobacillus stearothermophilus”. X-ray diffraction, 11 pockets (best druggability 0.82). MolNFT v1…
- PDB
- 5WTN
- Type
- protein
- Length
- 1,062 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Replication initiation and membrane attachment protein
- UniProt
- A0A0K2H6I1
- Pockets
- 11 · best druggability 0.82
Structure
x-ray diffraction · 4 distinct chains · 51% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Replication initiation and membrane attachment protein | protein | 268 | 53% helix, 13% strand | A0A0K2H6I1 |
| B | Replication initiation and membrane attachment protein | protein | 264 | 53% helix, 14% strand | A0A0K2H6I1 |
| C | Replication initiation and membrane attachment protein | protein | 265 | 50% helix, 14% strand | A0A0K2H6I1 |
| D | Replication initiation and membrane attachment protein | protein | 265 | 48% helix, 13% strand | A0A0K2H6I1 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1052 | 0.82 | 0.83 | 99 | empty |
| 2 | 125 | 0.71 | 0.92 | 33 | empty |
| 3 | 95 | 0.70 | 0.93 | 34 | empty |
| 4 | 273 | 0.52 | 0.75 | 35 | empty |
| 5 | 143 | 0.44 | 0.76 | 17 | empty |
Interfaces
6 interfaces between chains.
- A–B · 4313 Ų buried · 55 hydrogen bonds · protein-protein
- C–D · 4290 Ų buried · 47 hydrogen bonds · protein-protein
- A–C · 1646 Ų buried · 19 hydrogen bonds · protein-protein
- B–D · 1523 Ų buried · 17 hydrogen bonds · protein-protein
- A–D · 41 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5WTN · Crystal Structure Analysis of primosome protein DnaB (resiues 1-300) from Geobacillus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0K2H6I1
- Elsewhere: RCSB PDB 5WTN · PDBe 5WTN · UniProt A0A0K2H6I1
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