MolNFT v1 · #138758 · protein
Crystal structure of staphylococcus aureus sdre apo form
5WTA · Serine-aspartate repeat-containing protein E: “Crystal structure of staphylococcus aureus sdre apo form”. X-ray diffraction, 18 pockets (best druggability 0.77). MolNFT v1 #138758 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5WTA
- Type
- protein
- Length
- 1,258 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serine-aspartate repeat-containing protein E
- UniProt
- Q932F7
- Pockets
- 18 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Serine-aspartate repeat-containing protein E | protein | 315 | 5% helix, 52% strand | Q932F7 |
| C, D | Serine-aspartate repeat-containing protein E | protein | 314 | 6% helix, 52% strand | Q932F7 |
Pockets
18 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 907 | 0.77 | 0.80 | 78 | empty |
| 2 | 532 | 0.76 | 0.84 | 75 | empty |
| 3 | 625 | 0.76 | 0.82 | 76 | empty |
| 4 | 132 | 0.71 | 0.91 | 27 | empty |
| 5 | 649 | 0.70 | 0.78 | 60 | empty |
Interfaces
5 interfaces between chains.
- C–D · 1223 Ų buried · 21 hydrogen bonds · protein-protein
- A–B · 1211 Ų buried · 14 hydrogen bonds · protein-protein
- B–D · 347 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 245 Ų buried · 3 hydrogen bonds · protein-protein
- A–D · 45 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5WTA · Crystal Structure of Staphylococcus aureus SdrE apo form · the same entry in another collection · chain B against B, TM-score 1.00
- Q932F7 · AlphaFold monomer V2.0 prediction for serine-aspartate repeat- containing protein E… · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q932F7
- Elsewhere: RCSB PDB 5WTA · PDBe 5WTA · UniProt Q932F7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.