MolNFT v1 · #138756 · protein

FAS1-IV domain of human periostin

5WT7: “FAS1-IV domain of human periostin”. Solution nmr, 2 pockets (best druggability 0.59). MolNFT v1 #138756 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5WT7
Type: protein
Length: 140 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Periostin
UniProt: Q15063
Pockets: 2 · best druggability 0.59

Structure

solution nmr · 1 distinct chain · 28% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Periostin	protein	140	28% helix, 26% strand	Q15063

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	240	0.59	0.79	23	empty
2	58	0.56	0.89	23	empty

Compared structures

5WT7 · FAS1-IV domain of Human Periostin · the same entry in another collection · chain A against A, TM-score 1.00
Q15063 · AlphaFold monomer V2.0 prediction for periostin (Q15063) · a predicted model of the same protein · chain A against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15063
Elsewhere: RCSB PDB 5WT7 · PDBe 5WT7 · UniProt Q15063

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.