MolNFT v1 · #138645 · protein

Crystal structure of coconut allergen cocosin

5WPW · 11S globulin isoform 1: “Crystal structure of coconut allergen cocosin”. X-ray diffraction, 7 pockets (best druggability 0.76). MolNFT v1 #138645 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5WPW
Type: protein
Length: 756 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 11S globulin isoform 1
UniProt: A0A0R7UCU5
Pockets: 7 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 14% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	11S globulin isoform 1	protein	379	15% helix, 40% strand	A0A0R7UCU5
B	11S globulin isoform 1	protein	377	14% helix, 40% strand	A0A0R7UCU5

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	110	0.76	0.96	34	empty
2	93	0.75	0.97	28	empty
3	90	0.73	0.96	21	empty
4	247	0.71	0.86	38	empty
5	94	0.47	0.81	20	empty

Interfaces

1 interface between chains.

A–B · 2438 Å² buried · 34 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

5WPW · Crystal structure of coconut allergen cocosin · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0R7UCU5
Elsewhere: RCSB PDB 5WPW · PDBe 5WPW · UniProt A0A0R7UCU5

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