MolNFT v1 · #138634 · protein
Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from streptococcus pneumoniae bound to hmg-CoA and in a partially closed conformation
5WPK: “Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from streptococcus pneumoniae bound to…”. X-ray diffraction, 1 ligand (HMG). MolNFT v1 #138634 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5WPK
- Type
- protein
- Length
- 803 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0A0D6J7E8
- Ligands
- HMG
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 381 | — | A0A0D6J7E8 |
| B | — | protein | 422 | — | A0A0D6J7E8 |
Ligands and binding sites
- HMG · 3-hydroxy-3-methylglutaryl-coenzyme A · ligand · 2 copies · chains A, B
- GOL · Glycerol · additive · 3 copies · chains A, B
- PE4 · 2-{2-[2-(2-{2-[2-(2-ethoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5WPK · Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from Streptococcus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0D6J7E8
- Elsewhere: RCSB PDB 5WPK · PDBe 5WPK · UniProt A0A0D6J7E8
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