MolNFT v1 · #138616 · protein

Crystal structure of drosophila melanogaster scribble PDZ1 domain in complex with guk-holder

5WOU · Protein LAP4: “Crystal structure of drosophila melanogaster scribble PDZ1 domain in complex with guk-holder”. X-ray diffraction. MolNFT v1 #138616 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5WOU
Type: protein
Length: 103 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein LAP4; Guk-holder, isoform a
UniProt: Q7KRY7, Q9VE13

Structure

x-ray diffraction · 2 distinct chains · 15% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein LAP4	protein	95	16% helix, 44% strand	Q7KRY7
V	Guk-holder, isoform a	protein	8	0% helix, 38% strand	Q9VE13

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 7 copies · chains A, V
PGE · Triethylene glycol · additive · chains A, V

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–V · 511 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

5WOU · Crystal Structure of drosophila melanogaster Scribble PDZ1 domain in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Q7KRY7 · AlphaFold monomer V2.0 prediction for protein LAP4 (Q7KRY7) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7KRY7
Every structure of UniProt Q9VE13
Elsewhere: RCSB PDB 5WOU · PDBe 5WOU · UniProt Q7KRY7 · UniProt Q9VE13

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