MolNFT v1 · #138615 · protein
NMR solution structure of a-lytic protease using two 4D-spectra
5WOT · Alpha-lytic protease: “NMR solution structure of a-lytic protease using two 4D-spectra”. Solution nmr, 1 pocket (best druggability 0.47). MolNFT v1 #138615 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5WOT
- Type
- protein
- Length
- 198 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpha-lytic protease
- EC
- 3.4.21.12
- UniProt
- P00778
- Pockets
- 1 · best druggability 0.47
Structure
solution nmr · 1 distinct chain · 4% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-lytic protease (EC 3.4.21.12) | protein | 198 | 4% helix, 52% strand | P00778 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 122 | 0.47 | 0.79 | 27 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 5WOT · NMR solution structure of a-lytic protease using two 4D-spectra · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00778
- Elsewhere: RCSB PDB 5WOT · PDBe 5WOT · UniProt P00778
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