MolNFT v1 · #138519 · protein
Crystal structure of a pollen receptor kinase 3
5WLS · Pollen receptor-like kinase 3: “Crystal structure of a pollen receptor kinase 3”. X-ray diffraction, 1 ligand (NAG), 3 pockets (best druggability 0.66). MolNFT v1 #138519 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5WLS
- Type
- protein
- Length
- 416 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pollen receptor-like kinase 3
- EC
- 2.7.11.1
- UniProt
- Q9M1L7
- Ligands
- NAG
- Pockets
- 3 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 12% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Pollen receptor-like kinase 3 (EC 2.7.11.1) | protein | 208 | 12% helix, 22% strand | Q9M1L7 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.66 | 0.95 | 17 | empty |
| 2 | 111 | 0.43 | 0.77 | 25 | empty |
| 3 | 129 | 0.42 | 0.76 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 515 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide, 4 glycan (disulfide, N-glycosylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9M1L7
- Elsewhere: RCSB PDB 5WLS · PDBe 5WLS · UniProt Q9M1L7
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