MolNFT v1 · #13836 · protein

High resolution structure of recombinant dianthin antiviral protein-potent anti-HIV agent (complex with cyclic AMP)

1LPC · Dianthin 30: “High resolution structure of recombinant dianthin antiviral protein-potent anti-HIV agent (complex with…”. X-ray diffraction, 1 ligand (CMP), 1 pocket (best druggability 0.48). MolNFT v1 #13836 on GenesisL1: 3D…

PDB: 1LPC
Type: protein
Length: 254 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dianthin 30
EC: 3.2.2.22
UniProt: P24476
Ligands: CMP
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dianthin 30 (EC 3.2.2.22)	protein	254	39% helix, 22% strand	P24476

Ligands and binding sites

CMP · Adenosine-3',5'-cyclic-monophosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.48	0.80	18	CMP

Compared structures

1LPC · High resolution structure of recombinant dianthin antiviral protein-potent anti-HIV agent… · the same entry in another collection · chain A against A, TM-score 1.00
P24476 · AlphaFold monomer V2.0 prediction for ribosome-inactivating protein dianthin-30 (P24476) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P24476
Elsewhere: RCSB PDB 1LPC · PDBe 1LPC · UniProt P24476

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