MolNFT v1 · #138241 · protein
Matrix protein (M1) of infectious salmon anaemia virus
5WCO · NS2: “Matrix protein (M1) of infectious salmon anaemia virus”. X-ray diffraction, 5 pockets (best druggability 0.72). MolNFT v1 #138241 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5WCO
- Type
- protein
- Length
- 588 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NS2
- UniProt
- Q910W0
- Pockets
- 5 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 66% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | NS2 | protein | 196 | 66% helix, 1% strand | Q910W0 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 971 | 0.72 | 0.76 | 98 | empty |
| 2 | 378 | 0.65 | 0.79 | 33 | empty |
| 3 | 309 | 0.60 | 0.78 | 35 | empty |
| 4 | 214 | 0.53 | 0.77 | 27 | empty |
| 5 | 151 | 0.48 | 0.77 | 17 | empty |
Interfaces
2 interfaces between chains.
- B–C · 1295 Ų buried · 23 hydrogen bonds · protein-protein
- A–B · 973 Ų buried · 20 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5WCO · Matrix Protein (M1) of Infectious Salmon Anaemia Virus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q910W0
- Elsewhere: RCSB PDB 5WCO · PDBe 5WCO · UniProt Q910W0
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