MolNFT v1 · #138236 · protein
Crystal structure of human methyltransferase-like protein 13 in complex with sah
5WCJ: “Crystal structure of human methyltransferase-like protein 13 in complex with sah”. X-ray diffraction, 2 ligands (SAH, UNX), 2 pockets (best druggability 0.37). MolNFT v1 #138236 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5WCJ
- Type
- protein
- Length
- 222 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methyltransferase-like protein 13
- EC
- 2.1.1.-
- UniProt
- Q8N6R0
- Ligands
- SAH, UNX
- Pockets
- 2 · best druggability 0.37
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methyltransferase-like protein 13 (EC 2.1.1.-) | protein | 222 | 45% helix, 23% strand | Q8N6R0 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
- UNX · Unknown atom or ion · ion · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.37 | 0.79 | 11 | empty |
| 2 | 73 | 0.36 | 0.77 | 23 | SAH |
Compared structures
- 5WCJ · Crystal Structure of Human Methyltransferase-like protein 13 in complex with SAH · the same entry in another collection · chain A against A, TM-score 1.00
- Q8N6R0 · AlphaFold monomer V2.0 prediction for EEF1A lysine and N-terminal methyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8N6R0
- Elsewhere: RCSB PDB 5WCJ · PDBe 5WCJ · UniProt Q8N6R0
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