MolNFT v1 · #138108 · protein
Lipid a disaccharide synthase (lpxb)-6 solubilizing mutations
5W8N · Lipid-a-disaccharide synthase: “Lipid a disaccharide synthase (lpxb)-6 solubilizing mutations”. X-ray diffraction, 3 pockets (best druggability 0.51). MolNFT v1 #138108 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5W8N
- Type
- protein
- Length
- 369 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lipid-a-disaccharide synthase
- EC
- 2.4.1.182
- UniProt
- A0A140NAT1
- Pockets
- 3 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lipid-a-disaccharide synthase (EC 2.4.1.182) | protein | 369 | 54% helix, 15% strand | A0A140NAT1 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 238 | 0.51 | 0.75 | 39 | empty |
| 2 | 66 | 0.31 | 0.73 | 13 | empty |
| 3 | 62 | 0.28 | 0.73 | 14 | empty |
Compared structures
- 5W8N · Lipid A Disaccharide Synthase (LpxB)-6 solubilizing mutations · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A140NAT1
- Elsewhere: RCSB PDB 5W8N · PDBe 5W8N · UniProt A0A140NAT1
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