MolNFT v1 · #138026 · protein
Uca Fab (unbound) from 6649 lineage
5W6C · Uca Fab heavy chain: “Uca Fab (unbound) from 6649 lineage”. X-ray diffraction, 3 pockets (best druggability 0.61). MolNFT v1 #138026 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5W6C
- Type
- protein
- Length
- 439 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uca Fab heavy chain; Uca Fab light chain
- UniProt
- S6B2B6, Q6GMX4
- Pockets
- 3 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| H | Uca Fab heavy chain | protein | 225 | 9% helix, 50% strand | S6B2B6 |
| L | Uca Fab light chain | protein | 214 | 8% helix, 50% strand | Q6GMX4 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 515 | 0.61 | 0.74 | 58 | empty |
| 2 | 91 | 0.39 | 0.77 | 20 | empty |
| 3 | 66 | 0.35 | 0.78 | 18 | empty |
Interfaces
1 interface between chains.
- H–L · 1895 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 5W6C · UCA Fab (unbound) from 6649 Lineage · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt S6B2B6
- Every structure of UniProt Q6GMX4
- Elsewhere: RCSB PDB 5W6C · PDBe 5W6C · UniProt S6B2B6 · UniProt Q6GMX4
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