MolNFT v1 · #138002 · protein
Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.
5W5O: “Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.”. X-ray diffraction, 1 ligand (9XA). MolNFT v1 #138002 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5W5O
- Type
- protein
- Length
- 4,399 residues
- Chains
- 16
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O43353
- Ligands
- 9XA
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, P | — | protein | 275 | — | O43353 |
| M | — | protein | 276 | — | O43353 |
| N | — | protein | 272 | — | O43353 |
| O | — | protein | 276 | — | O43353 |
Ligands and binding sites
- 9XA · 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine · ligand · 16 copies · chains A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5W5O · Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory… · the same entry in another collection · chain P against P, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43353
- Elsewhere: RCSB PDB 5W5O · PDBe 5W5O · UniProt O43353
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