MolNFT v1 · #137989 · protein
Crystal structure of mycobacterium tuberculosis crp-fnr family transcription factor cmr (RV1675C), truncated construct
5W5B · Hth-type transcriptional regulator cmr: “Crystal structure of mycobacterium tuberculosis crp-fnr family transcription factor cmr (RV1675C), truncated…”. X-ray diffraction, 1 ligand (CL), 3 pockets (best druggability 0.57). MolNFT v1…
- PDB
- 5W5B
- Type
- protein
- Length
- 224 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hth-type transcriptional regulator cmr
- UniProt
- P9WMH4
- Ligands
- CL
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hth-type transcriptional regulator cmr | protein | 224 | 46% helix, 23% strand | P9WMH4 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 219 | 0.57 | 0.79 | 27 | empty |
| 2 | 77 | 0.43 | 0.80 | 19 | empty |
| 3 | 78 | 0.35 | 0.75 | 14 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 5W5B · Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr… · the same entry in another collection · chain A against A, TM-score 1.00
- P9WMH4 · AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator cmr (P9WMH4) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WMH4
- Elsewhere: RCSB PDB 5W5B · PDBe 5W5B · UniProt P9WMH4
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