MolNFT v1 · #137936 · protein

Cryo-electron microscopy structure of a TRPML3 ion channel

5W3S: “Cryo-electron microscopy structure of a TRPML3 ion channel”. Electron microscopy, 3 ligands (Y01, 3PE, NA). MolNFT v1 #137936 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5W3S
Type: protein
Length: 1,940 residues
Chains: 4
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: F6RG56
Ligands: Y01, 3PE, NA

Structure

electron microscopy · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	—	protein	485	—	F6RG56

Ligands and binding sites

Y01 · Cholesterol hemisuccinate · ligand · 12 copies · chains A, C, B, D
3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · ligand · 4 copies · chains A, B, C, D
NA · Sodium ion · metal · 6 copies · chains C, D, A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5W3S · Cryo-electron microscopy structure of a TRPML3 ion channel · the same entry in another collection · chain A against A, TM-score 1.00
F6RG56 · AlphaFold monomer V2.0 prediction for mucolipin-3 (F6RG56) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F6RG56
Elsewhere: RCSB PDB 5W3S · PDBe 5W3S · UniProt F6RG56

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