MolNFT v1 · #137742 · protein

Peroxisomal membrane protein PEX15

5VXV: “Peroxisomal membrane protein PEX15”. X-ray diffraction, 1 pocket (best druggability 0.41). MolNFT v1 #137742 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5VXV
Type: protein
Length: 217 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Peroxisomal membrane protein PEX15
UniProt: Q08215
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 76% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Peroxisomal membrane protein PEX15	protein	217	76% helix, 2% strand	Q08215

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.41	0.81	14	empty

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

5VXV · Peroxisomal membrane protein PEX15 · the same entry in another collection · chain A against A, TM-score 1.00
Q08215 · AlphaFold monomer V2.0 prediction for peroxisomal membrane protein PEX15 (Q08215) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q08215
Elsewhere: RCSB PDB 5VXV · PDBe 5VXV · UniProt Q08215

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