MolNFT v1 · #137441 · protein
Benzopiperazine bet bromodomain inhibitor in complex with BD1 of BRD4
5VOM: “Benzopiperazine bet bromodomain inhibitor in complex with BD1 of BRD4”. X-ray diffraction, 1 ligand (9GY). MolNFT v1 #137441 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5VOM
- Type
- protein
- Length
- 252 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O60885
- Ligands
- 9GY
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 126 | — | O60885 |
Ligands and binding sites
- 9GY · 3-[(2S)-1-acetyl-4-(furan-2-carbonyl)-2-methyl-1,2,3,4-tetrahydroquinoxalin-6-yl]-N-methylbenzamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5VOM · Benzopiperazine BET bromodomain inhibitor in complex with BD1 of Brd4 · the same entry in another collection · chain A against A, TM-score 1.00
- O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60885
- Elsewhere: RCSB PDB 5VOM · PDBe 5VOM · UniProt O60885
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