MolNFT v1 · #137012 · protein
X-ray structure of nuclear receptor ror-gammat ligand binding domain + SRC2 peptide
5VB3 · Nuclear receptor ror-gamma, SRC2 chimera: “X-ray structure of nuclear receptor ror-gammat ligand binding domain + SRC2 peptide”. X-ray diffraction, 1 ligand (NA), 3 pockets (best druggability 0.83). MolNFT v1 #137012 on GenesisL1…
- PDB
- 5VB3
- Type
- protein
- Length
- 259 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nuclear receptor ror-gamma, SRC2 chimera
- UniProt
- P51449
- Ligands
- NA
- Pockets
- 3 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 71% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear receptor ror-gamma, SRC2 chimera | protein | 259 | 71% helix, 4% strand | P51449 |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 294 | 0.83 | 0.93 | 36 | empty |
| 2 | 230 | 0.54 | 0.77 | 35 | empty |
| 3 | 68 | 0.39 | 0.79 | 15 | NA |
Compared structures
- 5VB3 · X-ray structure of nuclear receptor ROR-gammat Ligand Binding Domain + SRC2 peptide · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51449
- Elsewhere: RCSB PDB 5VB3 · PDBe 5VB3 · UniProt P51449
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