MolNFT v1 · #1370 · protein

DNA mismatch repair protein muth from E. COLI

1AZO: “DNA mismatch repair protein muth from E. COLI”. X-ray diffraction, 2 pockets (best druggability 0.53). MolNFT v1 #1370 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1AZO
Type: protein
Length: 214 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Muth
UniProt: P06722
Pockets: 2 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Muth	protein	214	33% helix, 20% strand	P06722

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 11 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	244	0.53	0.76	32	EDO
2	121	0.48	0.79	19	empty

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

1AZO · DNA mismatch repair protein muth from E. COLI · the same entry in another collection · chain A against A, TM-score 1.00
P06722 · AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muth (P06722) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06722
Elsewhere: RCSB PDB 1AZO · PDBe 1AZO · UniProt P06722

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.