MolNFT v1 · #136911 · protein
PCNA mutant R61A/D63A protein defective in gene silencing
5V7L · Proliferating cell nuclear antigen: “PCNA mutant R61A/D63A protein defective in gene silencing”. X-ray diffraction, 3 pockets (best druggability 0.39). MolNFT v1 #136911 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5V7L
- Type
- protein
- Length
- 255 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Proliferating cell nuclear antigen
- UniProt
- P15873
- Pockets
- 3 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 18% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proliferating cell nuclear antigen | protein | 255 | 18% helix, 44% strand | P15873 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 72 | 0.39 | 0.79 | 15 | empty |
| 2 | 58 | 0.36 | 0.78 | 15 | empty |
| 3 | 51 | 0.25 | 0.73 | 14 | empty |
Compared structures
- 5V7L · PCNA mutant R61A/D63A Protein Defective in Gene Silencing · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15873
- Elsewhere: RCSB PDB 5V7L · PDBe 5V7L · UniProt P15873
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