MolNFT v1 · #136592 · protein
Crystal structure of anti-anti-sigma factor phyr from bartonella quintana
5UXW · Sensory transduction regulatory protein: “Crystal structure of anti-anti-sigma factor phyr from bartonella quintana”. X-ray diffraction, 4 pockets (best druggability 0.59). MolNFT v1 #136592 on GenesisL1: 3D structure, binding sites…
- PDB
- 5UXW
- Type
- protein
- Length
- 491 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sensory transduction regulatory protein
- UniProt
- A0A0H3LUV4
- Pockets
- 4 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 61% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sensory transduction regulatory protein | protein | 246 | 61% helix, 11% strand | A0A0H3LUV4 |
| B | Sensory transduction regulatory protein | protein | 245 | 61% helix, 11% strand | A0A0H3LUV4 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 7 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 351 | 0.59 | 0.77 | 47 | empty |
| 2 | 181 | 0.46 | 0.75 | 21 | EDO |
| 3 | 166 | 0.44 | 0.74 | 23 | empty |
| 4 | 76 | 0.34 | 0.75 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 200 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 5UXW · Crystal Structure of Anti-anti-sigma factor PhyR from Bartonella quintana · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H3LUV4
- Elsewhere: RCSB PDB 5UXW · PDBe 5UXW · UniProt A0A0H3LUV4
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