Pig purple acid phosphatase complexed with phosphate in two coordination modes along with a bridging hydroxide ion

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 24% strand (DSSP).

Ligands and binding sites

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
• FE · Fe (III) ion · metal · 2 copies · chains A
• NA · Sodium ion · metal · chains A
• PO4 · Phosphate ion · ion · chains A
• OH · Hydroxide ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 1 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

• 5UQ6 · Pig purple acid phosphatase complexed with phosphate in two coordination modes along with… · the same entry in another collection · chain A against A, TM-score 1.00
• P09889 · AlphaFold monomer V2.0 prediction for tartrate-resistant acid phosphatase type 5 (P09889) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P09889
• Elsewhere: RCSB PDB 5UQ6 · PDBe 5UQ6 · UniProt P09889