Structure of rat neuronal nitric oxide synthase heme domain in complex with (rs)-3-[(2-amino-4-methylquinolin-7-YL)METHOXY]-5-(2- (METHYLAMINO)PROPYL)BENZONITRILE

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
• H4B · 5,6,7,8-tetrahydrobiopterin · ligand · 2 copies · chains A, B
• M4R · 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2R)-2-(methylamino)propyl]benzonitrile · ligand · 2 copies · chains A, B
• 8FD · 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2S)-2-(methylamino)propyl]benzonitrile · ligand · 2 copies · chains A, B
• ZN · Zinc ion · metal · chains A, B
• ACT · Acetate ion · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 5UNY · Structure of rat neuronal nitric oxide synthase heme domain in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

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• Every structure of UniProt P29476
• Elsewhere: RCSB PDB 5UNY · PDBe 5UNY · UniProt P29476