MolNFT v1 · #135984 · protein

Crystal structure of MUNC13-1 mun domain

5UF7 · Protein unc-13 homolog a: “Crystal structure of MUNC13-1 mun domain”. X-ray diffraction, 2 pockets (best druggability 0.39). MolNFT v1 #135984 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5UF7
Type: protein
Length: 530 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein unc-13 homolog a
UniProt: Q62768
Pockets: 2 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein unc-13 homolog a	protein	530	72% helix, 1% strand	Q62768

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	107	0.39	0.75	19	empty
2	53	0.33	0.78	13	empty

Compared structures

5UF7 · Crystal structure of MUNC13-1 mun domain · the same entry in another collection · chain A against A, TM-score 1.00
Q62768 · AlphaFold monomer V2.0 prediction for protein unc-13 homolog a (Q62768) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q62768
Elsewhere: RCSB PDB 5UF7 · PDBe 5UF7 · UniProt Q62768

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