MolNFT v1 · #135982 · protein

Structure of the effector protein sidk (LPG0968) from legionella pneumophila (domain-swapped dimer)

5UF5: “Structure of the effector protein sidk (LPG0968) from legionella pneumophila (domain-swapped dimer)”. X-ray diffraction, 4 pockets (best druggability 0.48). MolNFT v1 #135982 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 5UF5
Type: protein
Length: 516 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Effector protein sidk
UniProt: G8UUS6
Pockets: 4 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Effector protein sidk	protein	258	71% helix, 0% strand	G8UUS6

Ligands and binding sites

GOL · Glycerol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	114	0.48	0.79	24	empty
2	65	0.33	0.76	18	empty
3	84	0.31	0.73	19	empty
4	64	0.30	0.74	17	empty

Interfaces

1 interface between chains.

A–B · 1714 Å² buried · 27 hydrogen bonds · protein-protein

Compared structures

5UF5 · Structure of the effector protein SidK (lpg0968) from Legionella pneumophila… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G8UUS6
Elsewhere: RCSB PDB 5UF5 · PDBe 5UF5 · UniProt G8UUS6

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