MolNFT v1 · #135979 · protein
Crystal structure of ribose 5 phosphate isomerase a from neisseria gonorrhoeae
5UF2 · Ribose-5-phosphate isomerase a: “Crystal structure of ribose 5 phosphate isomerase a from neisseria gonorrhoeae”. X-ray diffraction, 2 ligands (NA, PO4), 1 pocket (best druggability 0.42). MolNFT v1 #135979 on GenesisL1: 3D…
- PDB
- 5UF2
- Type
- protein
- Length
- 223 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribose-5-phosphate isomerase a
- EC
- 5.3.1.6
- UniProt
- B4RL16
- Ligands
- NA, PO4
- Pockets
- 1 · best druggability 0.42
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribose-5-phosphate isomerase a (EC 5.3.1.6) | protein | 223 | 34% helix, 26% strand | B4RL16 |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
- PO4 · Phosphate ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 9 copies · chains A
- BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.42 | 0.81 | 19 | NA, PO4, EDO |
Compared structures
- 5UF2 · Crystal Structure of ribose 5 phosphate isomerase A from Neisseria gonorrhoeae · the same entry in another collection · chain A against A, TM-score 1.00
- B4RL16 · AlphaFold monomer V2.0 prediction for ribose-5-phosphate isomerase a (B4RL16) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4RL16
- Elsewhere: RCSB PDB 5UF2 · PDBe 5UF2 · UniProt B4RL16
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