MolNFT v1 · #135899 · protein
Mycobacterium tuberculosis toxin mazf-MT6
5UCT · Endoribonuclease MAZF3: “Mycobacterium tuberculosis toxin mazf-MT6”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.41). MolNFT v1 #135899 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5UCT
- Type
- protein
- Length
- 199 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endoribonuclease MAZF3
- EC
- 3.1.-.-
- UniProt
- P9WIH9
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endoribonuclease MAZF3 (EC 3.1.-.-) | protein | 99 | 24% helix, 39% strand | P9WIH9 |
| B | Endoribonuclease MAZF3 (EC 3.1.-.-) | protein | 100 | 27% helix, 41% strand | P9WIH9 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 125 | 0.41 | 0.76 | 18 | SO4 |
| 2 | 87 | 0.38 | 0.77 | 30 | empty |
Interfaces
1 interface between chains.
- A–B · 72 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WIH9
- Elsewhere: RCSB PDB 5UCT · PDBe 5UCT · UniProt P9WIH9
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