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MolNFT v1 · #135850 · protein

Crystal structure of the N-terminal domain (domain 1) of rctb, rctb-1- 124-L48M

5UBD · Rctb replication initiator protein: “Crystal structure of the N-terminal domain (domain 1) of rctb, rctb-1- 124-L48M”. X-ray diffraction, 2 pockets (best druggability 0.68). MolNFT v1 #135850 on GenesisL1: 3D structure, binding…

PDB
5UBD
Type
protein
Length
232 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Rctb replication initiator protein
UniProt
A0A085QGR2
Pockets
2 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BRctb replication initiator proteinprotein11642% helix, 16% strandA0A085QGR2

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15460.680.7844empty
2720.400.7926empty

Interfaces

1 interface between chains.

  • A–B · 515 Ų buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

  • 5UBD · Crystal structure of the N-terminal domain (domain 1) of RctB, RctB-1-124-L48M · the same entry in another collection · chain A against A, TM-score 1.00

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