MolNFT v1 · #135838 · protein

Crystal structure of the yeast nucleoporin

5UAZ · Nucleoporin NUP53: “Crystal structure of the yeast nucleoporin”. X-ray diffraction, 1 pocket (best druggability 0.43). MolNFT v1 #135838 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5UAZ
Type: protein
Length: 188 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoporin NUP53
UniProt: Q03790
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Nucleoporin NUP53	protein	94	34% helix, 26% strand	Q03790

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 2 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	114	0.43	0.77	25	empty

Interfaces

1 interface between chains.

A–B · 622 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

5UAZ · Crystal structure of the yeast nucleoporin · the same entry in another collection · chain A against A, TM-score 1.00
Q03790 · AlphaFold monomer V2.0 prediction for nucleoporin NUP53 (Q03790) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q03790
Elsewhere: RCSB PDB 5UAZ · PDBe 5UAZ · UniProt Q03790

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.