MolNFT v1 · #135770 · protein
Crystal structure of co-CAO1
5U8Y · Carotenoid oxygenase 1: “Crystal structure of co-CAO1”. X-ray diffraction, 1 ligand (CO), 20 pockets (best druggability 0.84). MolNFT v1 #135770 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5U8Y
- Type
- protein
- Length
- 1,989 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carotenoid oxygenase 1
- UniProt
- Q7S860
- Ligands
- CO
- Pockets
- 20 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, D | Carotenoid oxygenase 1 | protein | 497 | 8% helix, 38% strand | Q7S860 |
| C | Carotenoid oxygenase 1 | protein | 498 | 8% helix, 39% strand | Q7S860 |
Ligands and binding sites
- CO · Cobalt (II) ion · metal · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1035 | 0.84 | 0.85 | 107 | empty |
| 2 | 408 | 0.84 | 0.91 | 69 | empty |
| 3 | 935 | 0.84 | 0.85 | 104 | empty |
| 4 | 221 | 0.83 | 0.96 | 47 | empty |
| 5 | 515 | 0.83 | 0.89 | 70 | empty |
Interfaces
4 interfaces between chains.
- B–C · 1518 Ų buried · 36 hydrogen bonds · protein-protein
- A–D · 1513 Ų buried · 35 hydrogen bonds · protein-protein
- A–B · 414 Ų buried · 2 hydrogen bonds · protein-protein
- C–D · 362 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 5U8Y · Crystal structure of Co-CAO1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7S860
- Elsewhere: RCSB PDB 5U8Y · PDBe 5U8Y · UniProt Q7S860
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.