MolNFT v1 · #135756 · protein

Crystal structure of a protein of unknown function ECL_02571 involved in membrane biogenesis from enterobacter cloacae

5U8J · UPF0502 protein BFJ73_07745: “Crystal structure of a protein of unknown function ECL_02571 involved in membrane biogenesis from…”. X-ray diffraction, 1 ligand (CL), 8 pockets (best druggability 0.77). MolNFT v1 #135756 on GenesisL1…

PDB: 5U8J
Type: protein
Length: 671 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: UPF0502 protein BFJ73_07745
UniProt: A0A1B3EZY2
Ligands: CL
Pockets: 8 · best druggability 0.77

Structure

x-ray diffraction · 4 distinct chains · 45% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	UPF0502 protein BFJ73_07745	protein	171	43% helix, 10% strand	A0A1B3EZY2
B	UPF0502 protein BFJ73_07745	protein	170	43% helix, 10% strand	A0A1B3EZY2
C	UPF0502 protein BFJ73_07745	protein	171	46% helix, 9% strand	A0A1B3EZY2
D	UPF0502 protein BFJ73_07745	protein	159	47% helix, 11% strand	A0A1B3EZY2

Ligands and binding sites

CL · Chloride ion · ion · 2 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	445	0.77	0.86	55	empty
2	525	0.75	0.83	49	empty
3	376	0.63	0.78	57	empty
4	143	0.48	0.78	19	empty
5	144	0.44	0.76	21	empty

Interfaces

3 interfaces between chains.

A–C · 669 Å² buried · 1 hydrogen bond · protein-protein
A–B · 663 Å² buried · 19 hydrogen bonds · protein-protein
B–D · 608 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

5U8J · Crystal structure of a protein of unknown function ECL_02571 involved in membrane… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1B3EZY2
Elsewhere: RCSB PDB 5U8J · PDBe 5U8J · UniProt A0A1B3EZY2

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