MolNFT v1 · #135723 · protein
Crystal structure of the catalytic core of cbp
5U7G · Creb-binding protein: “Crystal structure of the catalytic core of cbp”. X-ray diffraction, 1 ligand (ZN), 16 pockets (best druggability 0.70). MolNFT v1 #135723 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5U7G
- Type
- protein
- Length
- 1,094 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Creb-binding protein
- UniProt
- Q8QZV8
- Ligands
- ZN
- Pockets
- 16 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Creb-binding protein | protein | 547 | 40% helix, 16% strand | Q8QZV8 |
Ligands and binding sites
- ZN · Zinc ion · metal · 8 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 414 | 0.70 | 0.82 | 49 | empty |
| 2 | 357 | 0.69 | 0.82 | 41 | empty |
| 3 | 100 | 0.67 | 0.91 | 23 | empty |
| 4 | 92 | 0.64 | 0.90 | 23 | empty |
| 5 | 196 | 0.52 | 0.78 | 24 | empty |
Compared structures
- 5U7G · Crystal Structure of the Catalytic Core of CBP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8QZV8
- Elsewhere: RCSB PDB 5U7G · PDBe 5U7G · UniProt Q8QZV8
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