MolNFT v1 · #135713 · protein

Chicken SLO2.2 in a closed conformation vitrified in the presence of 300 mm nacl

5U76 · Potassium channel subfamily T member 1: “Chicken SLO2.2 in a closed conformation vitrified in the presence of 300 mm nacl”. Electron microscopy, 13 pockets (best druggability 0.71). MolNFT v1 #135713 on GenesisL1: 3D structure…

PDB: 5U76
Type: protein
Length: 878 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Potassium channel subfamily T member 1
UniProt: Q8QFV0
Pockets: 13 · best druggability 0.71

Structure

electron microscopy · 1 distinct chain · 46% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Potassium channel subfamily T member 1	protein	878	46% helix, 12% strand	Q8QFV0

Pockets

13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	608	0.71	0.79	63	empty
2	341	0.70	0.83	26	empty
3	391	0.70	0.82	49	empty
4	245	0.60	0.80	24	empty
5	248	0.58	0.79	37	empty

Compared structures

5U76 · Chicken Slo2.2 in a closed conformation vitrified in the presence of 300 mM NaCl · the same entry in another collection · chain A against A, TM-score 1.00
Q8QFV0 · AlphaFold monomer V2.0 prediction for potassium channel subfamily T member 1 (Q8QFV0) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8QFV0
Elsewhere: RCSB PDB 5U76 · PDBe 5U76 · UniProt Q8QFV0

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