MolNFT v1 · #13562 · protein

Crystal structure of a conserved hypothetical protein AQ1575 from aquifex aeolicus

1LFP · Hypothetical protein AQ_1575: “Crystal structure of a conserved hypothetical protein AQ1575 from aquifex aeolicus”. X-ray diffraction, 2 pockets (best druggability 0.82). MolNFT v1 #13562 on GenesisL1: 3D structure, binding sites…

PDB: 1LFP
Type: protein
Length: 243 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein AQ_1575
UniProt: O67517
Pockets: 2 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hypothetical protein AQ_1575	protein	243	43% helix, 23% strand	O67517

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	785	0.82	0.85	69	empty
2	98	0.48	0.81	23	empty

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

1LFP · Crystal Structure of a Conserved Hypothetical Protein Aq1575 from Aquifex Aeolicus · the same entry in another collection · chain A against A, TM-score 1.00
O67517 · AlphaFold monomer V2.0 prediction for probable transcriptional regulatory protein AQ_1575… · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O67517
Elsewhere: RCSB PDB 1LFP · PDBe 1LFP · UniProt O67517

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