MolNFT v1 · #135503 · protein
E. COLI dihydropteroate synthase complexed with an 8-mercaptoguanine derivative
5U0Z: “E. COLI dihydropteroate synthase complexed with an 8-mercaptoguanine derivative”. X-ray diffraction, 1 ligand (7PM). MolNFT v1 #135503 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5U0Z
- Type
- protein
- Length
- 536 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0AC14
- Ligands
- 7PM
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 272 | — | P0AC14 |
| B | — | protein | 264 | — | P0AC14 |
Ligands and binding sites
- 7PM · (2R)-[(2-amino-6-oxo-6,9-dihydro-1H-purin-8-yl)sulfanyl](phenyl)acetic acid · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5U0Z · E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative · the same entry in another collection · chain A against A, TM-score 1.00
- P0AC14 · AlphaFold monomer V2.0 prediction for dihydropteroate synthase (P0AC14) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AC14
- Elsewhere: RCSB PDB 5U0Z · PDBe 5U0Z · UniProt P0AC14
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