MolNFT v1 · #135446 · protein
Crystal structure of human PDE2A in complex with (5S)-1-[(3-bromo-4- FLUOROPHENYL)CARBONYL]-3,3-difluoro-5-{5-methyl-[1,2,4]TRIAZOLO[1,5- A]PYRIMIDIN-7-YL}PIPERIDINE
5TZC: “Crystal structure of human PDE2A in complex with (5S)-1-[(3-bromo-4…”. X-ray diffraction, 3 ligands (7OJ, ZN, MG). MolNFT v1 #135446 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TZC
- Type
- protein
- Length
- 1,362 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O00408
- Ligands
- 7OJ, ZN, MG
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 343 | — | O00408 |
| C | — | protein | 340 | — | O00408 |
| D | — | protein | 336 | — | O00408 |
Ligands and binding sites
- 7OJ · (3-bromo-4-fluorophenyl)[(5S)-3,3-difluoro-5-(5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]methanone · ligand · 4 copies · chains A, B, C, D
- ZN · Zinc ion · metal · 4 copies · chains A, B, C, D
- MG · Magnesium ion · metal · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5TZC · Crystal Structure of human PDE2a in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00408
- Elsewhere: RCSB PDB 5TZC · PDBe 5TZC · UniProt O00408
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