MolNFT v1 · #135249 · protein
Crystal structure of catalytic domain of G9A with MS012
5TTF: “Crystal structure of catalytic domain of G9A with MS012”. X-ray diffraction, 4 ligands (7KZ, ZN, UNX). MolNFT v1 #135249 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TTF
- Type
- protein
- Length
- 1,063 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q96KQ7
- Ligands
- 7KZ, ZN, UNX, CL
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 266 | — | Q96KQ7 |
| B | — | protein | 269 | — | Q96KQ7 |
| C | — | protein | 266 | — | Q96KQ7 |
| D | — | protein | 262 | — | Q96KQ7 |
Ligands and binding sites
- 7KZ · N4-(1-methylpiperidin-4-yl)-N2-hexyl-6,7-dimethoxyquinazoline-2,4-diamine · ligand · 4 copies · chains A, B, C, D
- ZN · Zinc ion · metal · 16 copies · chains A, B, C, D
- UNX · Unknown atom or ion · ion · 5 copies · chains A, B, C, D
- CL · Chloride ion · ion · chains A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5TTF · Crystal structure of catalytic domain of G9a with MS012 · the same entry in another collection · chain B against B, TM-score 1.00
- Q96KQ7 · AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase EHMT2 (Q96KQ7) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96KQ7
- Elsewhere: RCSB PDB 5TTF · PDBe 5TTF · UniProt Q96KQ7
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