MolNFT v1 · #135241 · protein
T4 RNA ligase 1 (K99M)
5TT6: “T4 RNA ligase 1 (K99M)”. X-ray diffraction, 2 ligands (ATP, MG), 2 pockets (best druggability 0.76). MolNFT v1 #135241 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TT6
- Type
- protein
- Length
- 375 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- T4 RNA ligase 1
- EC
- 6.5.1.3
- UniProt
- P00971
- Ligands
- ATP, MG
- Pockets
- 2 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | T4 RNA ligase 1 (EC 6.5.1.3) | protein | 375 | 43% helix, 21% strand | P00971 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 814 | 0.76 | 0.80 | 85 | MG, ATP |
| 2 | 50 | 0.45 | 0.84 | 15 | empty |
Compared structures
- 5TT6 · T4 RNA Ligase 1 (K99M) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00971
- Elsewhere: RCSB PDB 5TT6 · PDBe 5TT6 · UniProt P00971
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