MolNFT v1 · #135235 · protein
Crystal structure of an oxidoreductase (short chain DEHYDROGENASE/REDUCTASE family) from burkholderia thailandensis
5TT0 · Oxidoreductase, short chain DEHYDROGENASE/REDUCTASE family: “Crystal structure of an oxidoreductase (short chain DEHYDROGENASE/REDUCTASE family) from burkholderia…”. X-ray diffraction, 2 ligands (NA, SO4), 5 pockets (best…
- PDB
- 5TT0
- Type
- protein
- Length
- 505 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Oxidoreductase, short chain DEHYDROGENASE/REDUCTASE family
- UniProt
- Q2T608
- Ligands
- NA, SO4
- Pockets
- 5 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oxidoreductase, short chain DEHYDROGENASE/REDUCTASE family | protein | 254 | 49% helix, 16% strand | Q2T608 |
| B | Oxidoreductase, short chain DEHYDROGENASE/REDUCTASE family | protein | 251 | 49% helix, 16% strand | Q2T608 |
Ligands and binding sites
- NA · Sodium ion · metal · chains B
- SO4 · Sulfate ion · ion · 5 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 19 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 470 | 0.72 | 0.81 | 51 | SO4, EDO |
| 2 | 380 | 0.57 | 0.75 | 41 | SO4, EDO |
| 3 | 126 | 0.45 | 0.77 | 25 | EDO |
| 4 | 108 | 0.39 | 0.75 | 22 | EDO |
| 5 | 92 | 0.34 | 0.74 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 1542 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 5TT0 · Crystal Structure of an Oxidoreductase (short chain dehydrogenase/reductase family) from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2T608
- Elsewhere: RCSB PDB 5TT0 · PDBe 5TT0 · UniProt Q2T608
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.