MolNFT v1 · #135234 · protein

Crystal structure of plasmodium vivax celtos

5TSZ · Pv cell-traversal protein: “Crystal structure of plasmodium vivax celtos”. X-ray diffraction, 1 ligand (NA), 3 pockets (best druggability 0.73). MolNFT v1 #135234 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5TSZ
Type: protein
Length: 390 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pv cell-traversal protein
UniProt: Q53UB7
Ligands: NA
Pockets: 3 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 79% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Pv cell-traversal protein	protein	130	79% helix, 0% strand	Q53UB7

Ligands and binding sites

NA · Sodium ion · metal · 3 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1168	0.73	0.75	58	empty
2	79	0.44	0.80	23	empty
3	85	0.31	0.72	16	empty

Interfaces

2 interfaces between chains.

A–B · 1530 Å² buried · 2 hydrogen bonds · protein-protein
B–C · 582 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

5TSZ · Crystal structure of Plasmodium vivax CelTOS · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q53UB7
Elsewhere: RCSB PDB 5TSZ · PDBe 5TSZ · UniProt Q53UB7

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