MolNFT v1 · #135214 · protein
The crystal structure of LPG2147 from legionella pneumophila
5TSC · Uncharacterized protein: “The crystal structure of LPG2147 from legionella pneumophila”. X-ray diffraction, 4 pockets (best druggability 0.65). MolNFT v1 #135214 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TSC
- Type
- protein
- Length
- 756 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- Q5ZTL4
- Pockets
- 4 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Uncharacterized protein | protein | 378 | 50% helix, 15% strand | Q5ZTL4 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 447 | 0.65 | 0.78 | 53 | empty |
| 2 | 75 | 0.48 | 0.82 | 23 | empty |
| 3 | 73 | 0.46 | 0.82 | 20 | empty |
| 4 | 57 | 0.29 | 0.75 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 446 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 5TSC · The crystal structure of Lpg2147 from Legionella pneumophila · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZTL4
- Elsewhere: RCSB PDB 5TSC · PDBe 5TSC · UniProt Q5ZTL4
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