MolNFT v1 · #134799 · protein
Crystal structure of a representative of class a beta-lactamase from bacteroides cellulosilyticus dsm 14838
5TFQ: “Crystal structure of a representative of class a beta-lactamase from bacteroides cellulosilyticus dsm 14838”. X-ray diffraction, 1 ligand (PO4), 2 pockets (best druggability 0.39). MolNFT v1 #134799 on GenesisL1: 3D structure…
- PDB
- 5TFQ
- Type
- protein
- Length
- 277 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-lactamase
- EC
- 3.5.2.6
- UniProt
- E2NI36
- Ligands
- PO4
- Pockets
- 2 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta-lactamase (EC 3.5.2.6) | protein | 277 | 45% helix, 22% strand | E2NI36 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 151 | 0.39 | 0.73 | 27 | PO4 |
| 2 | 58 | 0.32 | 0.77 | 14 | empty |
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 5TFQ · Crystal structure of a representative of class A beta-lactamase from Bacteroides… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E2NI36
- Elsewhere: RCSB PDB 5TFQ · PDBe 5TFQ · UniProt E2NI36
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