MolNFT v1 · #134725 · protein
Crystal structure of prefusion-stabilized bovine rsv fusion glycoprotein (single-chain DS2-V1 variant: strain 391-2 SC9 ds-CAV1 Q98C Q361C)
5TDL · Bovine prefusion rsv F glycoprotein: “Crystal structure of prefusion-stabilized bovine rsv fusion glycoprotein (single-chain DS2-V1 variant: strain…”. X-ray diffraction, 1 ligand (NAG), 3 pockets (best druggability 0.69). MolNFT v1…
- PDB
- 5TDL
- Type
- protein
- Length
- 450 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bovine prefusion rsv F glycoprotein
- UniProt
- P22167, P10104
- Ligands
- NAG
- Pockets
- 3 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bovine prefusion rsv F glycoprotein | protein | 450 | 29% helix, 33% strand | P22167, P10104 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 280 | 0.69 | 0.84 | 42 | empty |
| 2 | 57 | 0.27 | 0.74 | 18 | empty |
| 3 | 55 | 0.27 | 0.74 | 12 | empty |
Modifications
Observed in the structure: 8 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 5TDL · Crystal structure of prefusion-stabilized bovine RSV fusion glycoprotein (single-chain… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22167
- Every structure of UniProt P10104
- Elsewhere: RCSB PDB 5TDL · PDBe 5TDL · UniProt P22167 · UniProt P10104
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