MolNFT v1 · #13471 · protein

Monoclinic hen egg white lysozyme, thiocyanate complex

1LCN · Protein (lysozyme): “Monoclinic hen egg white lysozyme, thiocyanate complex”. X-ray diffraction, 1 ligand (SCN), 2 pockets (best druggability 0.35). MolNFT v1 #13471 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1LCN
Type: protein
Length: 258 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (lysozyme)
EC: 3.2.1.17
UniProt: P00698
Ligands: SCN
Pockets: 2 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein (lysozyme) (EC 3.2.1.17)	protein	129	41% helix, 11% strand	P00698

Ligands and binding sites

SCN · Thiocyanate ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.35	0.77	16	empty
2	58	0.31	0.76	17	empty

Interfaces

1 interface between chains.

A–B · 297 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

1LCN · Monoclinic hen egg white lysozyme, thiocyanate complex · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00698
Elsewhere: RCSB PDB 1LCN · PDBe 1LCN · UniProt P00698

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.