MolNFT v1 · #134679 · protein
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with butylthio-dadme-immucillin-a and chloride
5TC5: “Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with…”. X-ray diffraction, 2 ligands (BIG, CL). MolNFT v1 #134679 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TC5
- Type
- protein
- Length
- 825 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13126
- Ligands
- BIG, CL
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 286 | — | Q13126 |
| B | — | protein | 270 | — | Q13126 |
| C | — | protein | 269 | — | Q13126 |
Ligands and binding sites
- BIG · (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl) methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol · ligand · 3 copies · chains A, C, B
- CL · Chloride ion · ion · 4 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5TC5 · Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q13126 · AlphaFold monomer V2.0 prediction for S-methyl-5'-thioadenosine phosphorylase (Q13126) · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13126
- Elsewhere: RCSB PDB 5TC5 · PDBe 5TC5 · UniProt Q13126
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