MolNFT v1 · #134436 · protein

NMR structure of apo-form human tear lipocalin

5T43 · Lipocalin-1: “NMR structure of apo-form human tear lipocalin”. Solution nmr, 2 pockets (best druggability 0.68). MolNFT v1 #134436 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5T43
Type: protein
Length: 158 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lipocalin-1
UniProt: P31025
Pockets: 2 · best druggability 0.68

Structure

solution nmr · 1 distinct chain · 8% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lipocalin-1	protein	158	8% helix, 41% strand	P31025

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	421	0.68	0.80	40	empty
2	85	0.37	0.76	17	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5T43 · NMR Structure of Apo-form Human Tear Lipocalin · the same entry in another collection · chain A against A, TM-score 1.00
P31025 · AlphaFold monomer V2.0 prediction for lipocalin-1 (P31025) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31025
Elsewhere: RCSB PDB 5T43 · PDBe 5T43 · UniProt P31025

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