MolNFT v1 · #13441 · protein
Crystal structure of phosphoribosyl anthranilate isomerase (prai) in complex with reduced 1-(O-carboxyphenylamino)-1-deoxyribulose 5- phosphate (rcdrp)
1LBM: “Crystal structure of phosphoribosyl anthranilate isomerase (prai) in complex with reduced…”. X-ray diffraction, 1 ligand (137), 2 pockets (best druggability 0.58). MolNFT v1 #13441 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1LBM
- Type
- protein
- Length
- 194 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoribosyl anthranilate isomerase
- EC
- 5.3.1.24
- UniProt
- Q56320
- Ligands
- 137
- Pockets
- 2 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoribosyl anthranilate isomerase (EC 5.3.1.24) | protein | 194 | 41% helix, 23% strand | Q56320 |
Ligands and binding sites
- 137 · 1-(O-carboxy-phenylamino)-1-deoxy-D-ribulose-5-phosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 152 | 0.58 | 0.82 | 19 | empty |
| 2 | 127 | 0.44 | 0.77 | 22 | 137 |
Compared structures
- 1LBM · Crystal structure of phosphoribosyl anthranilate isomerase (prai) in complex with reduced… · the same entry in another collection · chain A against A, TM-score 1.00
- Q56320 · AlphaFold monomer V2.0 prediction for N-(5'-PHOSPHORIBOSYL)ANTHRANILATE isomerase (Q56320) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q56320
- Elsewhere: RCSB PDB 1LBM · PDBe 1LBM · UniProt Q56320
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