MolNFT v1 · #134337 · protein

Pelc L103M dodecamer from paraburkholderia phytofirmans, space group C2

5T11 · Uncharacterized protein: “Pelc L103M dodecamer from paraburkholderia phytofirmans, space group C2”. X-ray diffraction, 20 pockets (best druggability 0.77). MolNFT v1 #134337 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 5T11
Type: protein
Length: 1,632 residues
Chains: 12
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein
UniProt: B2T2U6
Pockets: 20 · best druggability 0.77

Structure

x-ray diffraction · 11 distinct chains · 26% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein	protein	135	26% helix, 36% strand	B2T2U6
B	Uncharacterized protein	protein	141	27% helix, 36% strand	B2T2U6
C	Uncharacterized protein	protein	134	26% helix, 36% strand	B2T2U6
D	Uncharacterized protein	protein	133	26% helix, 36% strand	B2T2U6
E, J	Uncharacterized protein	protein	139	26% helix, 37% strand	B2T2U6
F	Uncharacterized protein	protein	135	25% helix, 35% strand	B2T2U6
G	Uncharacterized protein	protein	137	26% helix, 36% strand	B2T2U6
H	Uncharacterized protein	protein	137	26% helix, 34% strand	B2T2U6
I	Uncharacterized protein	protein	135	27% helix, 35% strand	B2T2U6
K	Uncharacterized protein	protein	131	23% helix, 38% strand	B2T2U6
L	Uncharacterized protein	protein	136	24% helix, 36% strand	B2T2U6

Pockets

20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	795	0.77	0.81	141	empty
2	265	0.63	0.81	54	empty
3	219	0.62	0.82	34	empty
4	291	0.57	0.77	36	empty
5	261	0.56	0.77	32	empty

Interfaces

12 interfaces between chains.

B–D · 1089 Å² buried · 12 hydrogen bonds · protein-protein
A–E · 1046 Å² buried · 10 hydrogen bonds · protein-protein
G–K · 1029 Å² buried · 11 hydrogen bonds · protein-protein
H–J · 1011 Å² buried · 11 hydrogen bonds · protein-protein
I–K · 998 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 15 modified (engineered).

Compared structures

5T11 · PelC L103M dodecamer from Paraburkholderia phytofirmans, space group C2 · the same entry in another collection · chain K against K, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B2T2U6
Elsewhere: RCSB PDB 5T11 · PDBe 5T11 · UniProt B2T2U6

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